PRECLINICAL PUBLICATION · 2020

Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-beta/Smad3 signaling and promoting angiogenesis.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Fatty acid extracts from dried Lucilia sericata larvae

PMID 32194897 ↗2020Reported benefit

Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-beta/Smad3 signaling and promoting angiogenesis.

RatWound

Model: Rat acute cutaneous wound model

In a rat acute cutaneous wound model, fatty acid extracts promoted wound healing. Expression of c-Myc and Bcl-2 was up-regulated and expression of p53 and Bad was down-regulated after treatment.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.