THERAPY DOSSIER · th-e2cfb51b2ea1

Fatty acid extracts from dried Lucilia sericata larvae

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 32194897 ↗2020Reported benefit

Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-beta/Smad3 signaling and promoting angiogenesis.

RatWound

Model: Rat acute cutaneous wound model

In a rat acute cutaneous wound model, fatty acid extracts promoted wound healing. Expression of c-Myc and Bcl-2 was up-regulated and expression of p53 and Bad was down-regulated after treatment.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.

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