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PRECLINICAL PUBLICATION · 2020

Protective and Curative Effects of Aqueous Extract of (Edible Desert Truffle Specie) against Paracetamol Acute Toxicity in the Rat.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 32192374 ↗2020Mixed findings

Protective and Curative Effects of Aqueous Extract of (Edible Desert Truffle Specie) against Paracetamol Acute Toxicity in the Rat.

RatChemical/toxinPretreatment before paracetamol and co-treatment with paracetamol

Model: Paracetamol-induced acute liver and kidney injury

Liver and kidney biochemical parameters showed no significant variation between rats treated with paracetamol and or truffle extract. Histologically, pretreatment preserved normal liver and kidney architecture and co-treatment reduced paracetamol hepatotoxicity and renal toxicity, indicating protec…

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.