THERAPY DOSSIER · th-792fc029d9b1

Aqueous extract of edible desert truffle (Terfezia species), TBAE

Nutraceutical · Aqueous edible desert-truffle (Terfezia) extract; fungal extract.

Evidence & regulatory context

Mechanism: Aqueous edible desert-truffle (Terfezia) extract; fungal extract.
Target: Not recorded
Injury models: Chemical/toxin
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 32192374 ↗2020Mixed findings

Protective and Curative Effects of Aqueous Extract of (Edible Desert Truffle Specie) against Paracetamol Acute Toxicity in the Rat.

RatChemical/toxinPretreatment before paracetamol and co-treatment with paracetamol

Model: Paracetamol-induced acute liver and kidney injury

Liver and kidney biochemical parameters showed no significant variation between rats treated with paracetamol and or truffle extract. Histologically, pretreatment preserved normal liver and kidney architecture and co-treatment reduced paracetamol hepatotoxicity and renal toxicity, indicating protec…

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.

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