Histopathological Comparison of 2-Octyl Cyanoacrylate and Primary Suturing for Tongue Lacerations.
RatWoundSprague-DawleyFemalen = 24 rats, n = 6 per group across four groupsTopical application to the incision siteApplied at the time of injury
Model: Single linear incision on the midline dorsal tongue
Operative time was significantly shorter with the adhesive (p < 0.001). At day 5 moderate acute inflammatory cell infiltration and foreign body residue were more frequent with the adhesive, but by day 21 histopathology was indistinguishable from suturing (p > 0.05).
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