Evaluation of Neuroprotective Effect of Sevoflurane in Acute Traumatic Brain Injury: An Experimental Study in Rats.
RatTBIUnspecifiedSprague-DawleyMalen = 30 male Sprague-Dawley rats in three groupsInhalationApplied after induced trauma
Model: Diffuse acute traumatic brain injury model
Sevoflurane administration after acute traumatic brain injury did not prevent the development of oxidative stress or inflammation. Treated animals showed degenerative neuronal and glial changes, vascular enlargement and congestion, perivascular inflammatory infiltration, and positive VEGF and TNF-a…
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