Treatment of rats with spinal cord injury using human bone marrow-derived stromal cells prepared by negative selection.
RatSpinal cord injuryContusionMaleSub-occipital injection into the cisterna magnaOn average 2.3 million non-manipulated cells in 100 microli…One hour after lesion
Model: Spinal cord contusion injury at thoracic level T9/T10 using the Infinite Horizon impactor
Rats did not reject the human implants and showed no sickness behaviour or neuropathic pain. Compared with methylprednisolone, treated animals showed better recovery of motor deficits, with no difference in bladder control. Histology at ten weeks showed no difference in tissue sparing or astroglios…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.