Acute neuromodulation restores spinally-induced motor responses after severe spinal cord injury.
RatSpinal cord injuryContusionSprague-DawleyFemaleEpidural stimulation applied to four lumbosacral segments via a multi-electrode arrayAcutely after the contusive injury
Model: Calibrated contusive spinal cord injury at lumbar level
Repetitive Dynamic Stimulation restored spinally-evoked motor EMG responses that had been suppressed by the calibrated spinal cord contusion, whereas sham experiments showed no spontaneous recovery.
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