Does cryoneurolysis result in persistent motor deficits? A controlled study using a rat peroneal nerve injury model.
RatOtherLewisMalen = 30 ratsDirect application to the exposed common peroneal nerveCryoneurolysis was itself the intervention applied at the time of nerve exposure
Model: Common peroneal (mixed sensorimotor) nerve exposed bilaterally at the proximal lateral margin of the knee, with cryoneurolysis applied to one limb and sham treatment to the contralateral limb
Motor deficits in cryoneurolysis-treated limbs were present at 3 and 14 days but had resolved beyond one month. Bilateral sensory deficits followed the same time course and also resolved within one month. Axon counts trended lower at 3 days but were not significantly different at later time points,…
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