Procedure
4 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Acquired Brain Injury (Including Stroke) · Multiple Sclerosis · Spinal Cord Injury
Enrolment: 50 · Results not recorded
Phantom Limb Pain · Amputation, Surgical · Amputation, Traumatic
Enrolment: 12 · Results not recorded
Mastectomy · Limb Amputation · Knee Arthropathy · Shoulder Arthroplasty · VATS
Enrolment: 99 · Results not recorded
Rib Fractures · Pain, Acute · Pain, Chronic · Trauma Injury
Enrolment: 24 · Results not recorded
Chronic Musculoskeletal Pain · Cryo Analgesia · Cryoablation
Enrolment: 50 · Results not recorded
Chronic Sacroiliac Joint Pain
Enrolment: 30 · Results not recorded
Arthropathy of Knee · Pain, Joint · Arthritis Knee · Opioid Use
Enrolment: 0 · Results not recorded
Chronic Pain · Osteoarthritis, Knee
Enrolment: 87 · Results not recorded
Acute Postoperative Pain
Enrolment: 44 · Results not recorded
Stroke · Equinovarus Foot · Refractory Lower Limb Spasticity
Enrolment: 114 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Common peroneal (mixed sensorimotor) nerve exposed bilaterally at the proximal lateral margin of the knee, with cryoneurolysis applied to one limb and sham treatment to the contralateral limb
Motor deficits in cryoneurolysis-treated limbs were present at 3 and 14 days but had resolved beyond one month. Bilateral sensory deficits followed the same time course and also resolved within one month. Axon counts trended lower at 3 days but were not significantly different at later time points,…
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.
