Noncontact Phased-Array Ultrasound Facilitates Acute Wound Healing in Mice.
MouseWoundC57BL/6JMalen = 102 mice in total; 5 to 6 wounds per time point for histolo…Noncontact transcutaneous airborne ultrasound40 kHz ultrasound at 5.1 W/cm2, 10 Hz pulse frequency, outp…Started immediately after wounding
Model: Bilateral 6 mm full-thickness excisional dorsal skin wounds, silicone-stented to heal by secondary intention
Treated wounds epithelialised faster than sham wounds on day 5 (65 +/- 27 per cent versus 30 +/- 33 per cent closure) and day 7 (95 +/- 4 versus 81 +/- 9 per cent), showed greater CD31 area on day 2 (4.6 +/- 1.7 versus 2.2 +/- 1.0 per cent) and greater collagen density on day 5 (44 +/- 14 versus 28…
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