Glycyrrhizin Protects gamma-Irradiated Mice from Gut Bacteria-Associated Infectious Complications by Improving RNA Reduction in Macrophages of the Bacterial Translocation Site.

Glycyrrhizin Protects gamma-Irradiated Mice from Gut Bacteria-Associated Infectious Complications by Improving RNA Reduction in Macrophages of the Bacterial Translocation Site.

Model: 7 Gy gamma irradiation producing gastrointestinal acute radiation syndrome with gut bacteria-associated sepsis

Glycyrrhizin completely controlled mortality in mice exposed to 7 Gy, minimised bacterial translocation and subsequent sepsis, and prevented M2b macrophage polarisation in mesenteric lymph node macrophages.

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