Hyperoside alleviated-acetyl-para-amino-phenol-induced acute hepatic injury via Nrf2 activation.
MouseChemical/toxinOral
Model: Acetaminophen (N-acetyl-para-aminophenol) induced acute hepatic injury in mice, with parallel in vitro LO2 hepatocyte injury
Hyperoside dose-dependently reduced markers of acetaminophen-induced hepatic injury and oxidative stress, with the protective effect dependent on Nrf2.
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