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PEBBLE / ATLAS
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PRECLINICAL PUBLICATION · 2020

Ghrelin alleviates traumatic brain injury-induced acute lung injury through pyroptosis/NF-kB pathway.

Mouse / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31918060 ↗2020Reported benefit

Ghrelin alleviates traumatic brain injury-induced acute lung injury through pyroptosis/NF-kB pathway.

MouseTBIUnspecifiedC57BL/6MaleAfter induction of traumatic brain injury

Model: Traumatic brain injury in mice with secondary acute lung injury

Ghrelin improved lung histology, reduced lung vascular permeability and macrophage influx, and lowered proinflammatory and pyroptosis-related markers after traumatic brain injury.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.