Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury.

Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury.

Model: Acute spinal cord injury model in mice

Melatonin reduced reactive gliosis, proinflammatory cytokine expression and oxidative stress, and improved Basso mouse scale locomotor scores after spinal cord injury.

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