The Effects of Hyaluronic Acid on Traumatic Urethral Inflammation.
RatWoundWistarMalen = 40 adult male Wistar rats randomised into four groups (cont…IntraurethralHyaluronic acid 1.8% or 3%Applied during the acute period immediately following urethral injury
Model: Traumatic urethral injury and inflammation created by introducing a tiny hook and drawing it at the 12 o'clock position within the urethra
No group showed inflammation at the end of the study. Calcification, haemorrhage and stenosis occurred in all trauma groups. Tissue thickness increased significantly in the saline-treated group (p=0.004), but neither hyaluronic acid 1.8% nor 3% differed significantly from saline, indicating no bene…
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