Astrocytes-derived exosomes induce neuronal recovery after traumatic brain injury via delivering gap junction alpha 1-20 k.
MixedTBIFluid percussionfemale (per MeSH)Exosome transfer, route not stated
Model: Hydraulic (fluid pressure) traumatic brain injury in rats, with air pressure injury of cultured neurons in vitro
Astrocyte-derived exosomes carrying GJA1-20k were taken up by neurons, lowered apoptosis and improved mitochondrial function, with reduced brain damage confirmed in a rat traumatic brain injury model.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.45. Machine-extracted fields require source verification.