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PRECLINICAL PUBLICATION · 2019

Efficacy of human HC016 cell transplants on neuroprotection and functional recovery in a rat model of acute spinal cord injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31821721 ↗2019Reported benefit

Efficacy of human HC016 cell transplants on neuroprotection and functional recovery in a rat model of acute spinal cord injury.

RatSpinal cord injuryContusionWistarmaleCell graft to the injured cord48 hours after injury

Model: Contusion model of acute spinal cord injury in rats

HC016 cells showed superior survival to unpulsed adipose mesenchymal stem cells and produced statistically significant locomotor recovery with long-term neuroprotection, greater axonal regeneration and reduced glial reactivity.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.