Role of the antioxidant properties in the gastroprotective and gastric healing activity promoted by Brazilian green propolis and the healing efficacy of Artepillin C.
MixedChemical/toxinWistar rats; mouse strain not statedMaleOralPropolis extract 30 to 300 mg/kg in the acute ethanol model…Acute model: oral pre-treatment 1 h prior to ulcer induction. Chronic model: th…
Model: Acute gastric ulcer induced in rats by ethanol and chronic gastric ulcer induced by acetic acid; Artepillin C healing tested in mice with installed ulcers
Oral pre-treatment with the propolis extract at 100 and 300 mg/kg prevented ethanol-induced gastric epithelial damage, reduced superoxide dismutase activity by about 11% and 26% respectively, increased glutathione S-transferase activity by around 20% and catalase by 80%, and at 300 mg/kg reduced re…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.