PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2019

Possibilities and limitations of electrospun chitosan-coated polycaprolactone grafts for rotator cuff tear repair.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31670896 ↗2019Mixed findings

Possibilities and limitations of electrospun chitosan-coated polycaprolactone grafts for rotator cuff tear repair.

RatOtherLewisMalen = 51 rats in total, 17 per group (3 groups); 12 per group for…Surgical implantation at the repaired infraspinatus enthesis together with suture fixationAt the second (repair) surgery, 4 weeks after tendon detachment

Model: Chronic rotator cuff tear model: left infraspinatus tendon detached, followed 4 weeks later by repair surgery

Biomechanical parameters did not differ significantly between the CS-g-PCL and polyurethane implant groups, and median force at failure in both implant groups was lower than in the suture-fixed group. Histologically the CS-g-PCL implant showed no acute inflammation, good cell infiltration, ingrowth…

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.