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PRECLINICAL PUBLICATION · 2019

Raffia hookeri Ethanolic Pulp Extract Ameliorated Neuronal Damage and Brain Oxidative Stress Following Mechanical-Induced Traumatic Brain Injury in Rats.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31449279 ↗2019Reported benefit

Raffia hookeri Ethanolic Pulp Extract Ameliorated Neuronal Damage and Brain Oxidative Stress Following Mechanical-Induced Traumatic Brain Injury in Rats.

RatTBIWeight-drop / impact-accelerationWistarFemalen = 36 rats in 6 groups of 6Oral gavage100 mg/kgStarted after injury on experimental day 1

Model: Sharp and blunt traumatic brain injury induced by a modified weight-drop technique

Both injury types raised malondialdehyde and reduced glutathione, superoxide dismutase and catalase. Extract administration reduced oxidative damage and lessened subarachnoid and parenchymal haemorrhage in both sharp and blunt injury groups.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.