Histopathological Changes of Organs (Lungs, Liver, Kidney, and Brain) After Using Two Types of AgiCoat and Acticoat Nanosilver Dressings on Deep Second-Degree Burn in Rat.
RatBurnUnspecifiedSprague-DawleyMalen = 24 rats, 12 per groupTopical dressingApplied after burn induction
Model: Deep second-degree dorsal skin burn produced by a standard method under anaesthesia
Serum silver rose significantly above the reference level with both dressings. Hepatotoxicity was greater with AgiCoat than Acticoat, no pathological change was seen in other organs, and wound healing was faster with Acticoat.
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