Immunomodulatory effects of Calcitriol in acute spinal cord injury in rats.
RatSpinal cord injuryUnspecifiedSprague-DawleyFemale1 microgram/kgStarted after spinal cord injury, in the acute phase
Model: Acute spinal cord injury (specific model not stated in the abstract)
Calcitriol significantly improved BBB score at 12 weeks compared with injured controls, with more surviving ventral horn motor neurons, a significant regulatory effect on lymphocyte Division Index in response to myelin basic protein, and reduced IFN-gamma and IL-17A secretion and leukocyte infiltra…
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