Modulation of Spinal Nociceptive Transmission by Sub-Sensory Threshold Spinal Cord Stimulation in Rats After Nerve Injury
RatOtherSprague-Dawley (from PubMed MeSH indexing; not stated in the abstract)Male (from PubMed MeSH indexing; not stated in the abstract)n = n = 7-10 per group for stimulation at T13-L1; n = 8-10 per…Epidural, with the electrode placed at the T13-L1 or L2-L3 spinal levels; bipolar configurationSub-sensory threshold stimulation at 90% of A-beta threshol…After spinal nerve ligation; the interval between ligation and stimulation is n…
Model: L5 spinal nerve ligation producing peripheral neuropathic nerve injury
Traditional suprathreshold spinal cord stimulation at T13-L1 significantly reduced C-fibre evoked local field potentials. Sub-sensory threshold stimulation at 200 Hz and 500 Hz also reduced C-LFP, but to a lesser extent than traditional stimulation, whereas 1200 Hz and 10 000 Hz sub-threshold stimu…
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