New basic insights on the potential of a chitosan-based medical device for improving functional recovery after radical prostatectomy.
MixedOtherWistarMaleLocal implantation at the nerve repair site; chitosan coating or dissolution products applied to cultured cellsAt the time of median nerve injury and repair; organotypic cultures established…
Model: Standardised rat median nerve injury and repair using chitosan nerve guides and chitosan membranes; in vitro acutely axotomised autonomic neurones from primary sympathetic ganglia
Chitosan membranes significantly stimulated axon elongation from autonomic ganglia compared with control culture conditions, and chitosan coating and dissolution products significantly lowered proliferation of PC3, DU-145 and LN-Cap prostate cancer cells. In the rat median nerve model, tissue react…
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