Investigation into Possible Association of Oxandrolone and Heterotopic Ossification Following Burn Injury.
MixedBurnUnspecifiedAdministered after burn in the clinical cohort, with postburn day of initiation…
Model: Retrospective cohort of acutely burned adults admitted to a single burn centre between 2000 and 2014 with a heterotopic ossification risk factor score of 7 or higher, together with a standardised mouse burn plus tenotomy model of trauma-related heterotopic ossification
Patients who received oxandrolone had a higher crude incidence of elbow heterotopic ossification, but after adjustment for oxandrolone administration and duration, postburn day of initiation, heterotopic ossification risk score category, age, sex, race, burn size and year of injury there was no sig…
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