Rheinic acid ameliorates radiation-induced acute enteritis in rats through PPAR-gamma/NF-kappaB.
RatRadiationSprague-DawleyMaleOralAfter irradiation
Model: Acute radiation enteritis induced by a single 10 Gy abdominal X-ray dose delivered at 0.62 Gy/min
Rheinic acid promoted intestinal recovery, reduced bloody stool and histological damage, lowered pro-inflammatory cytokines, nitric oxide and malondialdehyde, raised superoxide dismutase and glutathione, and reduced apoptosis markers.
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.