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PRECLINICAL PUBLICATION · 2019

Ropivacaine inhibits pressure-induced lung endothelial hyperpermeability in models of acute hypertension.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 30822427 ↗2019Reported benefit

Ropivacaine inhibits pressure-induced lung endothelial hyperpermeability in models of acute hypertension.

RatOtherSprague-DawleyNot stated in abstractNot stated in abstract

Model: Isolated perfused lung with acute increases in left atrial pressure, and in vivo acute hypertension induced by noradrenaline

Ropivacaine prevented pressure-induced increases in the lung filtration coefficient, pulmonary oedema and nitric oxide production without altering pulmonary haemodynamics.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.