Fasting reduces oxidative stress, mitochondrial dysfunction and fibrosis induced by renal ischemia-reperfusion injury.
RatIschaemia-reperfusionRenaldietary intervention3 days of food deprivation3 days preoperatively
Model: Acute renal ischaemia-reperfusion injury
Three days of preoperative fasting protected against tubular damage and renal functional decline, preserved mitochondrial morphology and function and limited long-term tubulointerstitial fibrosis.
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