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PRECLINICAL PUBLICATION · 2018

Regeneration After Radiation- and Immune-Mediated Tissue Injury Is Not Enhanced by Type III Interferon Signaling.

Mouse / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 30503785 ↗2018No effect reported

Regeneration After Radiation- and Immune-Mediated Tissue Injury Is Not Enhanced by Type III Interferon Signaling.

MouseRadiationWild-type and IL-28 receptor alpha subunit-deficient (IL-28Ra) mice, cohoused

Model: Myeloablative total body irradiation causing thymic damage, and allogeneic haematopoietic stem cell transplantation after myeloablative total body irradiation causing graft-versus-host disease

Graft-versus-host disease course was comparable between IL-28Ra-deficient and wild-type mice, and PASylated IL-28A did not significantly modulate graft-versus-host disease or thymic regeneration after irradiation.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.