Synergistic therapeutic effects of Vitis vinifera extract and Silymarin on experimentally induced cardiorenal injury: The pertinent role of Nrf2.
RatChemical/toxinWistar albinoMalen = 60 adult male rats across 6 groups
Model: Doxorubicin-induced cardiorenal injury
Combined ethanolic Vitis vinifera extract and silymarin restored near-normal renal and cardiac histomorphology, significantly improved creatinine, blood urea nitrogen, lipid profile and high-sensitivity C-reactive protein, and raised Nrf2 mRNA expression.
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.