Investigation of the effects of hesperidin and chrysin on renal injury induced by colistin in rats.
RatChemical/toxinSprague-DawleyMale
Model: Colistin-induced nephrotoxicity (acute kidney injury)
Hesperidin and chrysin significantly reduced malondialdehyde and inflammatory markers and significantly increased glutathione, superoxide dismutase, catalase and glutathione peroxidase against colistin-induced renal injury. Cystatin C and calbindin D28K immunopositivity increased significantly with…
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