Effect of Diosmin/Hesperidin Combination on Clinical Outcomes in Patients With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
Enrolment: 120 · Results not recorded
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Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Polycystic Ovary Syndrome
Enrolment: 120 · Results not recorded
Cancer Patients
Enrolment: 100 · Results not recorded
Metabolic Syndrome · Obesity
Enrolment: 53 · Results not recorded
Multiple Sclerosis
Enrolment: 60 · Results not recorded
Cognitive Impairment · Old Age; Debility
Enrolment: 36 · Results not recorded
Metabolic Syndrome · Diabetic Neuropathy
Enrolment: 129 · Results not recorded
Fibromyalgia
Enrolment: 90 · Results not recorded
Blood Pressure · Hypertension
Enrolment: 67 · Results not recorded
3 studies reported at therapy level; 3 evidence entries itemised.
Model: Weight-drop spinal cord injury, 100 g/cm onto cord exposed at T7 to T10 by dorsal laminectomy
Hesperidin improved neurological scores at 24 hours, lowered IL-1beta and TNF-alpha, raised total antioxidant status, reduced haemorrhage, laceration, axonal and neuronal degeneration, necrosis, inflammation and oedema, and reduced caspase-3 positive apoptotic cells in both preconditioning and trea…
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.
Model: Chronic gastric ulcer induced by acetic acid
Hesperidin at 3 and 10 mg/kg accelerated ulcer healing by 34% and 62% respectively relative to vehicle (99.1 +/- 6.4 mm2), increased mucin production, preserved glutathione, normalised superoxide dismutase and catalase, increased glutathione-S-transferase activity by 35%, and reduced lipoperoxides…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.
Model: Colistin-induced nephrotoxicity (acute kidney injury)
Hesperidin and chrysin significantly reduced malondialdehyde and inflammatory markers and significantly increased glutathione, superoxide dismutase, catalase and glutathione peroxidase against colistin-induced renal injury. Cystatin C and calbindin D28K immunopositivity increased significantly with…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.