Reactive oxygen species stimulated pulmonary epithelial cells mediate the alveolar recruitment of FasLkiller B cells in LPS-induced acute lung injuries.

Reactive oxygen species stimulated pulmonary epithelial cells mediate the alveolar recruitment of FasLkiller B cells in LPS-induced acute lung injuries.

Model: Lipopolysaccharide induced acute lung injury

Scavenging reactive oxygen species reduced recruitment of FasL killer B cells into bronchoalveolar lavage fluid and attenuated lipopolysaccharide induced lung injury, indicating that reactive oxygen species act mainly as second messengers amplifying the immune response.

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