Nanotechnology in Wound Healing; Semisolid Dosage Forms Containing Curcumin-Ampicillin Solid Lipid Nanoparticles, in-vitro and in-vivo Characteristics.
MixedBurnContact / flameWistar rats; albino rabbitsMale rats; female rabbitsn = Rat group sizes and total not stated; the rabbit irritation…Topical (dermal)Ointment containing 255 mg and 192 mg lyophilised curcumin…
Model: Second degree dorsal burn wound created with cylindrical iron devices of 2.5 cm2 surface heated in boiling water at 98 plus or minus 1 degree C and applied for 10 s
Both the ointment and the gel containing curcumin and ampicillin solid lipid nanoparticles significantly increased the rate of burn wound healing relative to placebo bases and saline, with only very slight dermal irritation and no corrosive response in rabbits.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.