Topical application of stem bark ethanol extract of Sonapatha, Oroxylum indicum (L.) Kurz accelerates healing of deep dermal excision wound in Swiss albino mice.
MouseWoundSwiss albinoMale and femaleTopical application to the wound5%, 10%, 20% or 30% gel
Model: Deep dermal excision wound created on the shaved dorsum
Topical extract increased wound contraction and reduced mean wound healing time in a concentration dependent manner, with the greatest effect at 10%. DNA and neocollagen synthesis rose and lipid peroxidation fell, with maximum suppression of NF-kappa B and COX-II at 10%.
Extraction: extract · Supplied extraction confidence: 0.62. Machine-extracted fields require source verification.