THERAPY DOSSIER · th-b29bda92a174

Oroxylum indicum stem bark ethanol extract (OIE) gel

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 2

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT07220694 ↗NArecruiting

An 8-week Study Evaluating the Effects of a Dietary Supplement (Sabroxy) on Insulin Resistance and Cognitive Function in Subjects With MCI and Insulin Resistance

Insulin Resistance · Mild Cognitive Impairment · Cognitive Decline · Neurodegenerative Disorders

Enrolment: 140 · Results not recorded

NCT07189754 ↗NAcompleted

Effects of an Oroxylum Indicum Extract (Sabroxy) on Cognitive Function in Adults With Self-reported Mild Cognitive Impairment

Mild Cognitive Impairment (MCI) · Cognitive Dysfunction · Memory Problems

Enrolment: 70 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 30121235 ↗2018Reported benefit

Topical application of stem bark ethanol extract of Sonapatha, Oroxylum indicum (L.) Kurz accelerates healing of deep dermal excision wound in Swiss albino mice.

MouseWoundSwiss albinoMale and femaleTopical application to the wound5%, 10%, 20% or 30% gel

Model: Deep dermal excision wound created on the shaved dorsum

Topical extract increased wound contraction and reduced mean wound healing time in a concentration dependent manner, with the greatest effect at 10%. DNA and neocollagen synthesis rose and lipid peroxidation fell, with maximum suppression of NF-kappa B and COX-II at 10%.

Extraction: extract · Supplied extraction confidence: 0.62. Machine-extracted fields require source verification.

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