Protective effects of hyperbaric oxygen preconditioning against LPS-induced acute lung injury in rats.
RatEndotoxin/LPSSprague-Dawleymalen = 32 rats, 8 per group across 4 groupsPreconditioning before lipopolysaccharide injection
Model: Lipopolysaccharide-induced acute lung injury
Hyperbaric oxygen preconditioning lowered lung injury scores, lung water content, hydrogen peroxide and malondialdehyde levels and myeloperoxidase activity, while improving arterial partial pressure of oxygen and superoxide dismutase activity. It inhibited NF-kappa B p65 nuclear translocation and e…
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