PebbleAtlas
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PRECLINICAL PUBLICATION · 2018

PBMT and topical diclofenac as single and combined treatment on skeletal muscle injury in diabetic rats: effects on biochemical and functional aspects.

Rat / Crush

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29992491 ↗2018Reported benefit

PBMT and topical diclofenac as single and combined treatment on skeletal muscle injury in diabetic rats: effects on biochemical and functional aspects.

RatCrushLimb / muscle crushWistarMaleTranscutaneous laser irradiation of the injured muscle; topical application for diclofenacPhotobiomodulation 830 nm, continuous mode, power output 10…First treatment 1 h after the muscle trauma

Model: Single controlled trauma to the anterior tibialis muscle in rats with experimental diabetes mellitus

Photobiomodulation alone and combined with diclofenac lowered cyclooxygenase-2 expression and plasma prostaglandin E2 more than injury or diclofenac alone, and improved gait at all time points.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.