THERAPY DOSSIER · th-8047dfd139c7

Photobiomodulation therapy (830 nm low-level laser) alone or combined with topical diclofenac sodium

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Crush
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 10

1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06370910 ↗Injury indicationNAcompleted

Low-Level Laser Therapy vs Cryotherapy in Postpartum Perineal Pain

Episiotomy; Complications · Laceration

Enrolment: 56 · Results not recorded

NCT02582593 ↗NAcompleted

Revitalize Cognition: Transcranial Near Infrared Stimulation in Older Adults

Aging

Enrolment: 16 · Results not recorded

NCT05413993 ↗NAcompleted

Immediate Effect Of Photobiomodulation On pH And Salivary Flow

Xerostomia

Enrolment: 20 · Results not recorded

NCT02118155 ↗NAcompleted

Connective Tissue Graft With or Without Low Intensity Laser Therapy

Gingival Recession

Enrolment: 40 · Results not recorded

NCT06808178 ↗NAcompleted

Kinesio Taping and Low Level Laser Therapy in Post Mastectomy Lymphedema

Lymphedema · Breast Cancer Stage II

Enrolment: 90 · Results not recorded

NCT05753540 ↗NAcompleted

MLS LASER Therapy in Chronic Nonspecific Neck Pain

Chronic Non-specific Neck Pain

Enrolment: 47 · Results not recorded

NCT05116020 ↗NAcompleted

Swiss Chiropractic Cohort Study (Musculoskeletal Pain)

Musculoskeletal Pain

Enrolment: 568 · Results not recorded

NCT04518891 ↗NAunknown

Cognitive Functional Therapy in Chronic Nonspecific Low Back Pain

Chronic Low-back Pain

Enrolment: 152 · Results not recorded

NCT06610747 ↗NArecruiting

Home Care Monitoring vs Standard Care in Diabetic Macular Edema

Diabetic Macular Edema

Enrolment: 308 · Results not recorded

NCT05265416 ↗NAcompleted

Piezocision vs Low-level Laser Therapy in Upper Canine Retraction

Class II Malocclusion

Enrolment: 58 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 29992491 ↗2018Reported benefit

PBMT and topical diclofenac as single and combined treatment on skeletal muscle injury in diabetic rats: effects on biochemical and functional aspects.

RatCrushLimb / muscle crushWistarMaleTranscutaneous laser irradiation of the injured muscle; topical application for diclofenacPhotobiomodulation 830 nm, continuous mode, power output 10…First treatment 1 h after the muscle trauma

Model: Single controlled trauma to the anterior tibialis muscle in rats with experimental diabetes mellitus

Photobiomodulation alone and combined with diclofenac lowered cyclooxygenase-2 expression and plasma prostaglandin E2 more than injury or diclofenac alone, and improved gait at all time points.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

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