Naringin protects acrolein-induced pulmonary injuries through modulating apoptotic signaling and inflammation signaling pathways in mice.

Naringin protects acrolein-induced pulmonary injuries through modulating apoptotic signaling and inflammation signaling pathways in mice.

Model: Acute acrolein inhalation (10 ppm for 12 hours) induced pulmonary injury

Naringin given before acrolein exposure significantly improved airspace enlargement and lung inflammation and mitigated MAPK, p53 and NF-kappaB signalling markers as well as oxidative damage markers.

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