Enhanced Rotator-Cuff Repair Using Platelet-Rich Plasma Adsorbed on Branched Poly(ester urea)s.
RatOtherSprague-DawleyFemaleLocal implantation of a platelet-rich plasma-soaked nanofibre disc at the repair site, or local platelet-rich plasma injectionAt the time of surgical repair
Model: Acute rotator-cuff tear with surgical repair
The platelet-rich plasma-soaked disc group showed the highest stiffness at 84 days (16.8 +/- 5.8 N/mm) compared with suture repair only (13.5 +/- 3.8 N/mm), disc alone (11.8 +/- 3.8 N/mm) and platelet-rich plasma injection (12.2 +/- 2.6 N/mm), with greater collagen organisation at 21 and 84 days an…
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