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PRECLINICAL PUBLICATION · 2018

Intravenous Infusion of Mesenchymal Stem Cells Alters Motor Cortex Gene Expression in a Rat Model of Acute Spinal Cord Injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29901416 ↗2018Outcome unclear

Intravenous Infusion of Mesenchymal Stem Cells Alters Motor Cortex Gene Expression in a Rat Model of Acute Spinal Cord Injury.

RatSpinal cord injuryUnspecifiedSprague-DawleyMaleIntravenous infusionAfter spinal cord injury, with analysis at 3 days post-infusion

Model: Acute spinal cord injury

Infused mesenchymal stem cells altered the motor cortex gene expression signature at 3 days, and a set of behaviourally associated differentially expressed genes correlated with functional outcome, but the study did not itself establish a treatment effect size on function.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.