Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury.

Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury.

Model: Severe thoracic spinal cord compression

Phenelzine improved hind limb function, reduced astrogliosis, promoted axonal regrowth and sprouting, upregulated L1 expression and signalling, and lowered pro-inflammatory cytokine levels in the injured spinal cord during the acute inflammatory phase.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.