Ebselen protects mitochondrial function and oxidative stress while inhibiting the mitochondrial apoptosis pathway after acute spinal cord injury.

Ebselen protects mitochondrial function and oxidative stress while inhibiting the mitochondrial apoptosis pathway after acute spinal cord injury.

Model: Acute spinal cord injury

Ebselen increased the BBB locomotor score, raised glutathione, superoxide dismutase and catalase, increased mitochondrial ATP and Na-K-ATPase activity, reduced cytochrome c and Smac release and reduced apoptosis after spinal cord injury.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.