Effects of Mitochondrial Transplantation on Bioenergetics, Cellular Incorporation, and Functional Recovery after Spinal Cord Injury.
RatSpinal cord injuryContusionSprague-DawleyFemaleInjection into the injured spinal cord
Model: L1/L2 contusion spinal cord injury in rats
Mitochondrial transplantation maintained acute bioenergetics of the injured spinal cord in a concentration-dependent manner, and labelled mitochondria were incorporated into multiple resident cell types although not into neurons. Despite this, transplantation did not improve tissue sparing or long-…
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