Regulation of Autophagy Affects the Prognosis of Mice with Severe Acute Pancreatitis.
MouseChemical/toxinBALB/cIntraperitoneal injectionGiven after the onset of acute pancreatitis; tissues analysed 24 h after the la…
Model: Severe acute pancreatitis induced by L-arginine, or by cerulein plus lipopolysaccharide
3-Methyladenine ameliorated systemic organ injury in both severe acute pancreatitis models, impairing autophagic flux and reducing inflammatory activation and cytokine levels.
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