Arctigenin protects against liver injury from acute hepatitis by suppressing immune cells in mice.
MouseChemical/toxinBALB/cMale
Model: Concanavalin A (ConA)-induced acute hepatitis
Arctigenin reduced liver congestion and necroinflammation, improved hepatic ALT and AST, decreased hepatic infiltration of CD4 T cells, NKT cells and macrophages, and suppressed ConA-induced T lymphocyte proliferation, partly via enhanced IL-10 production, in a mouse model of ConA-induced acute hep…
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