Chitosan porous 3D scaffolds embedded with resolvin D1 to improve in vivo bone healing.
RatFractureFemurWistarMaleImplantation into the femoral defectAt the time of defect creation
Model: Rat femoral bone defect with scaffold implantation
Two months after implantation, chitosan scaffolds embedded with resolvin D1 increased new bone formation, trabecular thickness, collagen type I and the collagen I to collagen III ratio compared with chitosan scaffolds alone, indicating that pro-resolving mediator delivery during the acute inflammat…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.