Axonal regeneration of different tracts following transplants of human glial restricted progenitors into the injured spinal cord in rats.
RatSpinal cord injuryHemisection / partialSprague-DawleyFemalen = Hemisection 12 rats (8 transplant, 4 control); dorsal colum…Intraspinal injection into the lesion site5 microlitres of cell suspension into the hemisection and 3…Acute, immediately after the lesion was made
Model: Acute cervical C4 spinal cord injury, either dorsal column lesion or lateral hemisection
Grafts increased sensory, raphespinal and reticulospinal axon growth into the lesion but had no effect on coeruleospinal or rubrospinal axons, and no axons grew through the graft.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.